Parkinson's disease, a disorder of older persons, most commonly develops between the ages of 70-80 years. Unfortunately, in recent decades, the disease has "younger", and therefore it is not unusual for a parkinsonizma the sixth decade of life, or even sooner.
The disease progresses slowly over many years, and some patients still works for 15-20 years after onset. Parkinson's disease : causes disease Cause of the disease so far unknown. The disease is manifested by the loss of brain biologically active substances (mediators), responsible for motor function, and their deficit is the result of cell death of certain brain structures.
The first symptoms begin to emerge only in the deaths of 80% of these cells, which further proves how robust is the human body. Because of lack of these mediators all traffic patient parkinsonizmom are "poor", homogeneous, more primitive lost individuality propulsion capabilities, so at some stage, patients with this disease are very similar to each other.
Parkinson's Disease : signs of the disease first signs of illness are constraints and jitter, and must say that their combination is optional. Usually these feelings arise in the same hand, often on the right. The patient remarked that a hand shake at rest, and in this hand feel embarrassed hardly subtle movement : it becomes difficult locking buttons, eyes, count coins, etc. To a large extent, affected voice-it is small, illegible. Ambient may notice a slight change in terms of : it is becoming less expressive "losing face" glamour, looking more directly blink less often. Often when the disease emotional changes; But reducing motor disability loses motivation for any activity, even very interesting before the disease develops depression.
Parkinson's disease : The nature of treating the disease medication to be used at different stages depends on the clinical forms of the syndrome parkinsonizma, clinical features paintings and its dynamics, age, gender, somatic condition of the patient and opportunistic diseases. Treatment parkinsonizma polisistemny must take into account the nature of its manifestations in the form of propulsion, vegetative, mental, sensory, dissomnicheskih, neuroendocrine and other violations. The most comprehensive therapy should be based on an understanding of the etiology, pathogenesis and symptomatic treatment. Selecting a particular type of medication depends on the patient as well as the form of the disease and its manifestations.
Despite the fact that most current drugs in Parkinson's disease are at any stage of the disease, there are medications that are used only at some stage. The basic principle of choice is to maximize the benefits while minimizing complications from the treatment.
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